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高瑞霞  
研究领域(方向)

1.         先进分离材料的制备及其在药物分析、食品分析、环境分析中的应用

2.         分子识别和分子印迹聚合物

3.         纳米药物诊疗一体化

4.         生物样品高效分离与高灵敏度检测

个人及工作简历

1.         2019.11-今,访问学者,耶鲁大学,化工与环境学院

2.         2016.01-今,副教授,博士生导师,402com永利1站,理学院化学系

3.         2012.07-2015.12,讲师,402com永利1站,理学院化学系

4.         2009.09-2012.06,博士,南开大学,化学学院化学系

5.         2006.09-2009.06,硕士,南开大学,化学学院化学系

6.         2001.09-2005.07,学士,山西师范大学,化学与材料科学学院化学系

科研项目

1.         分子印迹磁性纳米材料用于饮用水中雌情化物质高效检测和快速去除的研究,21305107,国家自然科学基金,主持

2.         多模板分子印迹磁性纳米材料的制备及其应用,2017JM2010,陕西省自然科学基础研究项目,主持

3.         高吸附容量紫杉醇分子印迹磁性微/纳米材料的制备和应用研究,2020JM-066,陕西省自然科学基础研究项目,主持

4.         新型高选择性磁性纳米材料在前列腺癌内分泌治疗中的应用研究,xjj2017028,中央高校基本科研业务费,主持

5.         单(多)印迹层多模板分子印迹磁性纳米球的制备和应用,2014M562388,中国博士后科学基金,主持

6.         磁性分子印迹纳米材料应用于环境及饮用水样中类固醇雌激素的分离和检测,xjj2013041,中央高校基本科研业务费,主持

学术及科研成果、专利、论文

1. 代表性论文

1)    Ruixia Gao*, Xihui Cui, Yi Hao, Lili Zhang, Dechun Liu, Yuhai Tang*. A highly-efficient imprinted magnetic nanoparticle for selective separation and detection of 17β-estradiol in milk. Food Chem., 2016, 194: 1040-1047. ESI高被引论文、热点论文)

2)    Ruixia Gao*, Yi Hao, Lili Zhang, Xihui Cui, Dechun Liu, Min Zhang, Yuhai Tang*, Yuansuo Zheng. A facile method for protein imprinting on directly carboxyl-functionalized magnetic nanoparticles using non-covalent template immobilization strategy. Chem. Eng. J., 2016, 284: 139-148. ESI高被引论文)

3)    Yi Hao, Ruixia Gao*, Dechun Liu, Gaiyan He, Yuhai Tang, Zengjun Guo*. Selective extraction and determination of chlorogenic acid in fruit juices using hydrophilic magnetic imprinted nanoparticles. Food Chem., 2016, 200: 215-222. ESI高被引论文)

4)    Yue Wang, Wenchang Zhao, Xuemeng Tian, Huijia Song, Ruixia Gao*, Xiaoshuang Tang, Xiaojing Zhang, Yi Hao*, Yuhai Tang. High-efficiency recognition and detection of sulindac in sewage using hydrophilic imprinted resorcinol-formaldehyde resin magnetic nano-spheres as SPE adsorbents combined with HPLC. Chem. Eng. J., 2020, 123716.

5)    Luyao Gao, Yuhai Tang, Chaofeng Wang, Lu Yao*, Junjie Zhang, Ruixia Gao*, Xiaoshuang Tang, Tie Chong, Huan Zhang. Highly-efficient amphiphilic magnetic nanocomposites based on a simple sol-gel modification for adsorption of phthalate esters. J. Colloid Interf. Sci., 2019, 552: 142-152.

6)    Yayun Zhao, Yuhai Tang, Jun He, Yuan Xu, Ruixia Gao*, Junjie Zhang, Tie Chong, Li Wang, Xiaoshuang Tang*. Surface imprinted polymers based on amino-hyperbranched magnetic nanoparticles for selective extraction and detection of chlorogenic acid in Honeysuckle tea. Talanta, 2018, 181: 271-277.

7)    Xiaoshuang Tang, Feng Li, Jing Jia, Chao Yang, Wei Liu, Ben Jin, Xinyang Wang, Ruixia Gao*, Dalin He, Peng Guo*. Synthesis of magnetic molecularly imprinted polymers with excellent biocompatibility for the selective separation and inhibition of testosterone in prostate cancer cells. Int. J. Nanomed., 2017, 12: 2979-2993.

8)    Yi Hao, Ruixia Gao*, Dechun Liu, Bianbian Zhang, Yuhai Tang, Zengjun Guo*. Preparation of biocompatible molecularly imprinted shell on superparamagnetic iron oxide nanoparticles for selective depletion of bovine hemoglobin in biological sample. J. Colloid Interf. Sci., 2016, 470: 100-107.

9)    Yi Hao, Ruixia Gao*, Dechun Liu, Yuhai Tang, Zengjun Guo*. Selective extraction of gallic acid in pomegranate rind using surface imprinting polymers over magnetic carbon nanotubes. Anal. Bioanal. Chem., 2015, 407: 7681-7690.

10)Yi Hao, Ruixia Gao*, Lu Shi, Dechun Liu, Yuhai Tang, Zengjun Guo*. Water-compatible magnetic imprinted nanoparticles served as solid-phase extraction sorbents for selective determination of trace 17beta-estradiol in environmental water samples by liquid chromatography. J. Chromatogr. A, 2015, 1396: 7-16.

11)Ruixia Gao*, Xinru Mu, Yi Hao, Lili Zhang, Junjie Zhang, Yuhai Tang*. Combination of surface imprinting and immobilized template techniques for preparation of core-shell molecularly imprinted polymers based on directly amino-modified Fe3O4 nanoparticles for specific recognition of bovine hemoglobin. J. Mater. Chem. B, 2014, 2: 1733-1741.

12)Ruixia Gao*, Xinru Mu, Junjie Zhang, Yuhai Tang*. Specific recognition of bovine serum albumin using superparamagnetic molecularly imprinted nanomaterials prepared by two-stage core-shell sol-gel polymerization. J. Mater. Chem. B, 2014, 2: 783-792.

2. 授权发明专利

1)         高瑞霞,赵雅韵,闫庆,封芳,杨梦瑶,张军杰,一种多巴胺及其代谢物分子印迹磁性纳米球及其制备方法和应用,授权专利号:ZL 201811197700.9,授权公告日:2020.03.26

2)         高瑞霞,赵雅韵,张军杰,唐玉海,一种氨基超支化的绿原酸分子印迹磁性纳米球及其制备方法和应用,授权专利号:ZL 201710415341.9,授权公告日:2019.09.24

3)         高瑞霞,张丽丽,赵思奇,唐玉海,一种表面聚多巴胺修饰的磁性碳纳米管的制备方法,授权专利号:ZL 201410265049.X,授权公告日:2016.06.08

4)         高瑞霞,郝旖,张军杰,唐玉海,一种表面醛基功能化的磁性纳米粒子的制备方法,授权专利号:ZL 201310647625.2,授权公告日:2015.12.02

5)         高瑞霞,郝旖,张军杰,唐玉海,一种磁性多模板类固醇雌激素分子印迹纳米球的制备方法,授权专利号:ZL 201310466119.3,授权公告日:2015.08.26

6)         高瑞霞,慕欣茹,张军杰,唐玉海,一种磁性双模板蛋白质分子印迹纳米粒子及其制备方法,授权专利号:ZL 201310461379.1,授权公告日:2015.07.01

3. 科研获奖

1)荣获2019年度陕西省自然科学奖二等奖,第一完成人

2)荣获2019年度陕西省高等学校科学技术奖一等奖,第一完成人

联系方式
电子邮箱:ruixiagao@xjtu.edu.cn
联系电话:18209293226
联系地址:陕西省咸阳市秦都区钓台街道交大创新港19号楼4122室
更新日期:2020-08-26